JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
The use of fetal bovine acellular dermal matrix for management of chronic wounds
Abstract
Aims: In the treatment of chronic wounds, tissue growth must be addressed and optimized. The purpose of this study is to investigate the use of the regenerative medicinal product Fetal Bovine Acellular Dermal Matrix (FBADM) in chronic wounds.
Methods: The patients were chosen sporadically and randomly based on availability to FBADM. Patients were assessed for adequate perfusion, debridement was performed, and wounds were ensured to be free of infection. FBADM was placed in the wound bed covered with a non-adherent contact layer, and a hydrogel sheet was placed to maintain adequate moisture. Offloading or compression was used as clinically indicated. Patients were then followed weekly. Digital photography was used to visually document healing progress.
Results: After 1-3 weeks wounds managed with FBADM had improved characteristics and healthy vascularized tissue that subsequently epithelialized from wound margins or grafted with split thickness skin grafts. Of the 14 wounds we achieved 69% complete healing, 24% non-complete healing after 12 weeks of FBADM application. 7% of the wounds needed skin graft surgery.
Conclusion: We found FBADM to be useful for treatment regimen of diabetic foot and leg ulcers, venous leg ulcers, surgical wounds, and wounds being prepared for skin grafting.

Keywords : Chronic wounds, extracellular matrix, tissue engineering, skin substitutes

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Article available in :
Volume 6, Issue 4, 2023
Page : 713-719
https://doi.org/10.32322/jhsm.1261658
Article Information
Received : 07 Mar 2023
Accepted : 08 Haz 2023
Published : 30 Tem 2023
Corresponding Author :

Tuna Gümüş: Department of Undersea and Hyperbaric Medicine, Kartal Dr. Lütfi Kırdar City Hospital, University of Health Sciences, İstanbul, Turkey

[email protected]
Citation : Gümüş T, Vlad LG. The use of fetal bovine acellular dermal matrix for management of chronic wounds. J Health Sci Med. 2023;6(4):713-719

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