JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Ultrasonic shear-wave elastography: a novel method for assessing the tumor grade in endometrial cancer: a prospective study
Abstract
Aims: To evaluate the diagnostic performance of the real time shear-wave elastography in patients with endometrial cancer in terms of tumor grade and myometrial invasion depth preoperatively.
Methods: In this prospective observational study, forty-eight women who were diagnosed with endometrioid type endometrium cancer in our gynecologic oncology clinic of a tertiary hospital between September 2020-January 2021 in Turkey. All patients underwent an ultrasonographic shear-wave measurements. Mean shear-wave values were measured from the tumor itself. Mean elasticity values were assessed in terms of tumor grade and myometrial invasion depth.
Results: The median [%25-%75] shearwave value of the participants was 29.45kPa (5.02-167.21). Shear-wave value for grade 3 endometrial cancer showed a statistically significant difference compared to grade 1 and 2 shear-wave values (p<0.001). To determine the myometrial invasion depth, lymph node involvement, lympho-vascular stromal invasion and cervical stromal invasion statues, shear-wave measurements did not show a significant result (p>0.05). ROC curve analysis showed significant results to determine the myometrial invasion depth and grade 3 endometrial cancer with the mean shear-wave cut-off values of 28.29 kPa and 57 kPa respectively (p<0.001).
Conclusion: Real-time shear-wave elastography is a promising tool to predict the grade 3 tumors and deep myometrial invasion in endometrial cancer patients.

Keywords : Endometrial cancer, Shear-wave elastography, shear-wave, tumor grade, grade 3 endometrial cancer

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Article available in :
Volume 6, Issue 5, 2023
Page : 987-992
https://doi.org/10.32322/jhsm.1330040
Article Information
Received : 19 Tem 2023
Accepted : 30 Ağu 2023
Published : 28 Eyl 2023
Corresponding Author :

Emre Destegül: Department of Obstetrics and Gynecology, Adana City Training and Research Hospital, University of Health Science, Adana, Turkey

[email protected]
Citation : Destegül E, Çakır Pekoz B, Seyfettinoğlu S, Baş S, Adıgüzel FI, Narin MA. Ultrasonic shear-wave elastography: a novel method for assessing the tumor grade in endometrial cancer: a prospective study. J Health Sci Med. 2023;6(5):987-992.

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