JHSM

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
The effect of nasal septum deviation type on the systemic inflammatory index and blood markers of inflammation
Aims: The aim of this study was to identify the changes in blood markers of inflammation and the systemic immune inflammatory index in patients with nasal septum deviation (NSD). An additional aim was to determine if there was a significant difference in the findings according to septum deviation type.
Methods: This retrospective study included 321 patients diagnosed with NSD via physical examination and CT (NSD group), and 101 healthy controls. Standard complete blood count was performed. Main blood parameters and mean platelet volume (MPV), the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), and the systemic immune inflammatory index (SII) were recorded. NSD was classified as 3 types according to Dreher classification, and the types were compared to each other and the control group.
Results: The hemoglobin level, and platelet and neutrophil counts were significantly higher in the NSD group than in the control group (P<0.001 for each). The MPV, NLR, PLR, and SII were also significantly higher in the NSD group (P<0.001 for each). There was a significant increase in all blood markers of inflammation as the degree of septum deviation increased (P<0.001 for each).
Conclusion: Blood markers of inflammation are significantly elevated in patients with NSD. The SII value can indicate an inflammatory condition in these patients. The degree of septum deviation can affect the degree of inflammation.


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Volume 6, Issue 5, 2023
Page : 1069-1073
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