JHSM

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

EndNote Style
Index
Original Article
Comparison of preoperative MRI and surgical findings in perianal fistulas and factors affecting recurrence
Aims: Anal fistula occurs most commonly when the anal glands become obstructed and infected in the intersphincteric plane. Although it has a high recurrence rates, its treatment is surgical. Magnetic resonance imaging (MRI) is the gold standard for accurate preoperative evaluation of the patient and detection of the relationship to the muscle groups that provide continence. The aim of this study was to evaluate the compatibility of MRI with surgery and to determine the parameters effective on recurrence.
Methods: Primary perianal fistulas with MRI between 2016 and 2023 were retrospectively evaluated. Patient demographics were documented. Fistula classifications according to MRI findings, abscess locations, internal and external opening regions on MRI were compared with surgical findings. The surgical procedures performed were documented. Univariate and multivariate evaluations of recurrence performed by Cox regression analysis. Disease-free survival data were analyzed.
Results: A total of 180 cases with a mean age of 43.75±12.57 years were included in the study. At the end of MRI, there were 69 (38.3%) cases with an fistula external orifice > 3 cm. The largest group in Parks classification were intersphincteric patients with 127 (66.7%), 52 (28.9%) of the patients were in the complex group. The level of agreement between surgery and MRI internal opening was 13.4% and statistically significant (Kappa coefficient of agreement 0.134; p<0.01). Total recurrence was observed in 33(18.3%) patients. Recurrence was statistically significant in patients with external orifice >3 cm, transsphincteric, complex and patients requiring loose seton in surgery (p=0.001, p=0.001, p=0.001, p=0.001, p=0.007; p<0.01 respectively).
Conclusion: In our study, we found that the recurrence rate was higher in patients with an external orifice of more than 3 cm, transsphincteric, 3-4th degree complex fistulas, and patients with loose setons.


1. Zhao WW, Yu J, Shu J, et al. Precise and comprehensive evaluationof perianal fistulas, classification and related complications usingmagnetic resonance imaging. Am J Transl Res. 2023;15(5):3674-3685.
2. Limura E, Giordano P. Modern management of anal fistula. WorldJ Gastroenterol. 2015;21(1):12-20.
3. Wlodarczyk M, Wlodarczyk J, Sobolewska-WlodarczykA, Trzcinski R, Dziki L, Fichna J. Current concepts in thepathogenesis of cryptoglandular perianal fistula. J Int Med Res.2021;49(2):300060520986669.
4. Iqbal N, Tozer PJ, Fletcher J, et al. Getting the most out of MRIin perianal fistula: update on surgical techniques and radiologicalfeatures that define surgical options. Clin Radiol. 2021;76(10):784.e17-e25.
5. Vial M, Par&eacute;s D, Pera M, Grande L. Faecal incontinence afterseton treatment for anal fistulae with and without surgicaldivision of internal anal sphincter: a systematic review. ColorectalDis. 2010;12(3):172-178.
6. Vo D, Phan C, Nguyen L, Le H, Nguyen T, Pham H. The role ofmagnetic resonance imaging in the preoperative evaluation ofanal fistulas. Sci Rep. 2019;9(1):17947.
7. Liang C, Lu Y, Zhao B, Du Y, Wang C, Jiang W. Imaging of analfistulas: comparison of computed tomographic fistulography andmagnetic resonance imaging. Korean J Radiol. 2014;15(6):712-723.
8. Balcı S, Onur MR, Karaosmanoğlu AD, et al. MRI evaluation ofanal and perianal diseases. Diagn Interv Radiol. 2019;25(1):21-27.
9. Konan A, Onur MR, &Ouml;zmen MN. The contribution of preoperativeMRI to the surgical management of anal fistulas. Diagn IntervRadiol. 2018;24(6):321-327.
10. Bayrak M, Altintaş Y, Alabaz &Ouml;, &Ccedil;elİktaş M. Contribution ofpreoperative magnetic resonance imaging in diagnosis and surgicaltreatment of anal fistula. Cukurova Med J. 2020;45(3):1210-1216.
11. O&#39;Malley RB, Al-Hawary MM, Kaza RK, Wasnik AP, Liu PS,Hussain HK. Rectal imaging: part 2, Perianal fistula evaluationon pelvic MRI--what the radiologist needs to know. AJR Am JRoentgenol. 2012;199(1):W43-W53.
12. Sahni VA, Ahmad R, Burling D. Which method is best for imagingof perianal fistula?. Abdom Imaging. 2008;33(1):26-30.
13. Buchanan G, Halligan S, Williams A, et al. Effect of MRI on clinicaloutcome of recurrent fistula-in-ano. Lancet. 2002;360(9346):1661-1662.
14. Morris J, Spencer JA, Ambrose NS. MR imaging classificationof perianal fistulas and its implications for patient management.Radiographics. 2000;20(3):623-637.
15. Liu X, Wang Z, Ren H, Wang Z, Li J. Accuracy of magneticresonance imaging in defining dentate line in anal fistula. BMCMed Imaging. 2022;22(1):1-11.
16. Madany AH, Murad A, Kabbash M, Ahmed H. Magneticresonance imaging in the workup of patients with perianalfistulas. Egypt J Radiol Nucl Med. 2023;54(1):1-16.
17. Singh K, Singh N, Thukral C, Singh KP, Bhalla V. Magneticresonance imaging (MRI) evaluation of perianal fistulae withsurgical correlation. J Clin Diagn Res. 2014;8(6):RC01-RC4.
18. Jacob TJ, Perakath B, Keighley MR. Surgical intervention foranorectal fistula. Cochrane Database Syst Rev. 2010;(5):CD006319.
19. Lei C, Li C, Liu M, Song Z, Li C, Liu Z. Proximal anal sinusresection as an alternative to fistulectomy and seton for reducingrecurrence of anal fistulas: a retrospective study. Ann Palliat Med.2021;10(12):12273-12279.
20. Mei Z, Wang Q, Zhang Y, et al. Risk Factors for Recurrence afteranal fistula surgery: a meta-analysis. Int J Surg. 2019;69:153-164.
Volume 6, Issue 6, 2023
Page : 1380-1386
_Footer