JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
The impacts of comorbid diseases on surgical and clinical outcomes in spondylolisthesis surgery
Abstract
Aims: Management of comorbidities has a significant bearing on clinical outcomes from surgery, especially in the context of wound healing and pain management. This study aims to compare surgical patients with comorbidity (case group) and without (control group) based on recovery outcomes.
Methods: Surgical patients n=150 were enrolled patients in the case group (n=75), and control group (n=75). We collected and compared baseline demographic data, preoperative and postoperative pain levels based on the Visual Analogue Scale, discharge outcomes and assessment of wound healing. Factors affecting wound healing were evaluated using multivariate logistic regression, and predictors of postoperative pain were examined with multivariate linear regression.
Results: Demographic data revealed that the groups were comparable regarding age (p=0.122) and gender (p=0.758). The case group did have a higher mean body-mass index (BMI) of 28.9±3.4 than the control group mean BMI, which was 25.7±2.9; (p<0.001). Preoperative 7.5±1.2 vs 6.8±1.1, (p=0.001) and postoperative 4.8±1.5 vs 3.2±10, (p<0.001), pain scores were significantly greater in the case group. This is especially true for the case group, as only 40% were discharged in less than or equal to 24 hours compared with 73.3% of control (p<0.001). Cure of all wounds occurred in 90.7% of controls compared with 66.7% of cases (p<0.001), and delayed healing was significantly greater in cases (33.3% vs 9.3%, p=0.002). The case group had an odds ratio of 0.25 (p<0.001) for complete wound healing on multivariate analysis whereas group status, age, BMI and diabetes mellitus were significant postoperative pain predictors.
Conclusion: These findings highlight the need to direct resources towards preoperative evaluations before spondylolisthesis surgery and strategies in recovery after surgery for patients with diseases/disorders relevant to common problems seen.

Keywords : Spondylolisthesis, comorbid diseases, wound healing, spine surgery

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Article available in :
Volume 8, Issue 2, 2025
Page : 167-173
https://doi.org/10.32322/jhsm.1604696
Article Information
Received : 26 Ara 2024
Accepted : 13 Oca 2025
Published : 21 Mar 2025
Corresponding Author :

Fahri Eryılmaz: Department of Neurosurgery, Faculty of Medicine, Bozok University, Yozgat, Turkiye

[email protected]
Citation : Eryılmaz F, Yurdakul G. The impacts of comorbid diseases on surgical and clinical outcomes in spondylolisthesis surgery. J Health Sci Med. 2025;8(2):167-173.

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