JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

ISSN: Active
eISSN: 2636-8579
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Submit Manuscript

Index
Original Article
Evolution of Leiomyomas with FIGO classification regarding parity, body-mass index and admission symptoms
Abstract
Aims: To examine the outcomes of leiomyomas classified by FIGO in relation to the demographic, clinical, and laboratory characteristics of patients who underwent laparotomic myomectomy.
Methods: A total of 199 patients were found between September 2019 and September 2023 according to the criteria for study. Data were analyzed and compared in terms of FIGO leiomyoma classification, leiomyoma size, admission symptoms, body-mass index (BMI) and parity. All demographical and operational features were compared in each group for issues including leiomyomas >8 cm, <8 cm; single or multiple leiomyomas; BMI >30, <30; multiparous and nulliparous patients. Moreover, patients’ admission symptoms as abnormal uterine bleeding, pelvic pain and compression were also recorded and compared.
Results: The mean leiomyoma size, compression symptoms and pelvic pain of those with abnormal uterine bleeding was 8.5±3.2 cm, 9.6±3.1 cm, and 10.9±3.6 cm; respectively. The mean leiomyoma size of individuals with pelvic pain was significantly larger than that of those with abnormal uterine bleeding (p<0.05). Nulliparous patients exhibited a higher incidence of multiple myomas than multiparous patients. Nulliparous patients experienced a lower incidence of abnormal uterine hemorrhage than multiparous patients; however, the incidence of pelvic pain and pressure symptoms was more common (p=0.013). The mean leiomyoma size of those with BMI <30 and BMI ?30 was 9.8±3.6 cm, and 9.2±3.1 cm; respectively. No statistically significant difference was observed between these groups in terms of mean leiomyoma size, operation time, hospital stay and postoperative complications (p>0.05).
Conclusion: When evaluating laparotomic myomectomy patients, the patient’s parity status, location and size of the leiomyoma should be taken into consideration before surgery.

Keywords : Leiomyomas, parity, FIGO classification, laparotomic myomectomy

Download Article


1. Baird DD, Dunson DB, Hill MC, Cousins D, Schectman JM. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol. 2003;188(1):100-107. doi:10. 1067/mob.2003.99
2. Serden SP, Brooks PG. Treatment of abnormal uterine bleeding with the gynecologic resectoscope. J Reprod Med. 1991;36(10):697-699.
3. Ahrendt HJ, Tylkoski H, Rabe T, et al. Prevalence of uterine myomas in women in Germany: data of an epidemiological study. Arch Gynecol Obstet. 2016;293(6):1243-1253. doi:10.1007/s00404-015-3930-8
4. Giuliani E, As-Sanie S, Marsh EE. Epidemiology and management of uterine fibroids. Int J Gynaecol Obstet. Apr 2020;149(1):3-9. doi:10.1002/ijgo.13102
5. Borah BJ, Nicholson WK, Bradley L, Stewart EA. The impact of uterine leiomyomas: a national survey of affected women. Am J Obstet Gynecol. 2013;209(4):319-320. doi:10.1016/j.ajog.2013.07.017
6. Stewart EA. Clinical practice. Uterine fibroids. N Engl J Med. 2015; 372(17):1646-1655. doi:10.1056/NEJMcp1411029
7. Munro MG, Critchley HO, Fraser IS, Group FMDW. The FIGO classification of causes of abnormal uterine bleeding in the reproductive years. Fertil Steril. 2011;95(7):2204-2208. doi:10.1016/j.fertnstert.2011. 03.079
8. Wamsteker K, Emanuel MH, de Kruif JH. Transcervical hysteroscopic resection of submucous fibroids for abnormal uterine bleeding: results regarding the degree of intramural extension. Obstet Gynecol. 1993; 82(5):736-740.
9. Marshall LM, Spiegelman D, Barbieri RL, et al. Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol. 1997;90(6):967-973. doi:10.1016/s0029-7844(97)00534-6
10. Stewart EA, Friedman AJ. Steroidal treatment of myomas: preoperative and long-term medical therapy. Copyright&copy; 1992 by Thieme Medical Publishers, Inc.; 1992:344-357.
11. Sato F, Miyake H, Nishi M, Kudo R. Fertility and uterine size among Asian women undergoing hysterectomy for leiomyomas. Int J Fertil Womens Med. 2000;45(1):34-37.
12. Ross RK, Pike MC, Vessey MP, Bull D, Yeates D, Casagrande JT. Risk factors for uterine fibroids: reduced risk associated with oral contraceptives. Br Med J (Clin Res Ed). 1986;293(6543):359-362. doi:10. 1136/bmj.293.6543.359
13. Parazzini F, Negri E, La Vecchia C, Chatenoud L, Ricci E, Guarnerio P. Reproductive factors and risk of uterine fibroids. Epidemiology. 1996; 7(4):440-442. doi:10.1097/00001648-199607000-00018
14. Marshall LM, Spiegelman D, Goldman MB, et al. A prospective study of reproductive factors and oral contraceptive use in relation to the risk of uterine leiomyomata. Fertil Steril. 1998;70(3):432-439. doi:10.1016/s0015-0282(98)00208-8
15. Wachsberg RH, Kurtz AB, Levine CD, Solomon P, Wapner RJ. Real-time ultrasonographic analysis of the normal postpartum uterus: technique, variability, and measurements. J Ultrasound Med. Mar 1994;13(3):215-221. doi:10.7863/jum.1994.13.3.215
16. Hsu KF, Pan HA, Hsu YY, Wu CM, Chung WJ, Huang SC. Enhanced myometrial autophagy in postpartum uterine involution. Taiwan J Obstet Gynecol. 2014;53(3):293-302. doi:10.1016/j.tjog.2013.01.030
17. Foth D, R&ouml;hl FW, Friedrich C, et al. Symptoms of uterine myomas: data of an epidemiological study in Germany. Arch Gynecol Obstet. 2017; 295(2):415-426. doi:10.1007/s00404-016-4239-y
18. Monle&oacute;n J, Ca&ntilde;ete ML, Caballero V, et al. Epidemiology of uterine myomas and clinical practice in Spain: an observational study. Eur J Obstet Gynecol Reprod Biol. 2018;226:59-65. doi:10.1016/j.ejogrb.2018. 05.026
19. Lacey CG. Myoma of the uterus. Current gynecologic and obstetric diagnosis and treatment 4<sup>th</sup> ed Lange, Los Altos. 1982.
20. Puri K, Famuyide AO, Erwin PJ, Stewart EA, Laughlin-Tommaso SK. Submucosal fibroids and the relation to heavy menstrual bleeding and anemia. Am J Obstet Gynecol. 2014;210(1):38 e1-7. doi:10.1016/j.ajog. 2013.09.038
21. David M, Pitz CM, Mihaylova A, Siedentopf F. Myoma-associated pain frequency and intensity: a retrospective evaluation of 1548 myoma patients. Eur J Obstet Gynecol Reprod Biol. 2016;199:137-140. doi:10.1016/ j.ejogrb.2016.02.026
22. Cinar M, Tokmak A, Guzel AI, et al. Association of clinical outcomes and complications with obesity in patients who have undergone abdominal myomectomy. J Chin Med Assoc. 2016;79(8):435-439. doi:10. 1016/j.jcma.2016.02.008
23. Wen KC, Horng HC, Wang PH. Hemorrhage: A strong indicator for myomectomy-related complication. J Chin Med Assoc. 2016;79(8):413-414. doi:10.1016/j.jcma.2016.02.004
24. G&uuml;rb&uuml;z T, Yardımcı O, Udum S, G&uuml;nay T. The relationship between body-mass index and clinical complications among patients undergoing myomectomy. J Surg Med. 2020;4(11):1027-1030.
Article available in :
Volume 8, Issue 2, 2025
Page : 319-324
https://doi.org/10.32322/jhsm.1596426
Article Information
Received : 05 Ara 2024
Accepted : 03 Mar 2025
Published : 21 Mar 2025
Corresponding Author :

Fikriye Işıl Adıgüzel: Department of Obstetrics and Gynecology, Adana City Training and Research Hospital, University of Health Science, Adana, Turkey

[email protected]
Citation : Yağmacı G, Işıl Adıgüzel F, Uysal G. Evolution of Leiomyomas with FIGO classification regarding parity, body-mass index and admission symptoms. J Health Sci Med. 2025;8(2):319-324.

Read: -4
Cited: 0
Download : 35
_Footer