JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Predictors of no-reflow after coronary stenting in patients with high thrombus burden
Abstract
Aims: In this study, we aimed to reveal the predictors of no-reflow after coronary stenting in patients with high thrombus burden.
Methods: Patients with acute myocardial infarction who underwent stenting of a coronary lesion with high thrombus burden in the same session between February 2020 and July 2022 in our center were included in this retrospective study. High thrombus burden was accepted as Thrombolysis in Myocardial Infarction (TIMI) grade 4 or 5 thrombus. No-reflow was accepted as TIMI grade ?2 flow at the end of the procedure. Multivariate logistic regression analysis was executed to ascertain the predictors of no-reflow.
Results: Of the 485 patients included in the study, 407 (83.9%) did not develop no-reflow. Of the 78 (16.1%) patients who developed no-reflow at the end of the procedure, 61 had TIMI 2, 10 had TIMI 1, and 7 had TIMI 0 flow. Age [odds ratio (OR) 1.051; 95% confidence interval (CI) 1.021-1.082; p=.001], accumulated thrombus proximal to the occlusion (OR 3.318; 95% CI 1.176-9.365; p=.023), reference vessel diameter (RVD) greater than 4 mm (OR 2.569; 95% CI 1.005-6.565; p=.049), and TIMI flow grade after wiring or small balloon dilation (OR 0.108; 95% CI 0.065-0.181; p<.001) were the independent predictors of no-reflow.
Conclusion: Older age, accumulated thrombus proximal to the occlusion, RVD greater than 4 mm, and the absence of TIMI grade 3 flow after wiring or small balloon dilation may be associated with an increased risk of no-reflow after coronary stenting in patients with high thrombus burden.

Keywords : No-reflow, coronary stenting, high thrombus burden

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Article available in :
Volume 8, Issue 2, 2025
Page : 345-349
https://doi.org/10.32322/jhsm.16151566
Article Information
Received : 02 Oca 2025
Accepted : 12 Mar 2025
Published : 21 Mar 2025
Corresponding Author :

Ufuk Yıldırım: Department of Cardiology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkiye

[email protected]
Citation : Yıldırım U, Çoksevim M, Kara A, Altınbaş A, Başer MH. Predictors of no-reflow after coronary stenting in patients with high thrombus burden. J Health Sci Med. 2025;8(2):345-349.

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