JHSM
Journal of Health Sciences and Medicine

Journal of Health Sciences and Medicine (JHSM) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Comparison of blood count values in children with obstructive sleep apnea due to adenoid hypertrophy and those without apnea
Abstract
Aims: This study aimed to investigate whether adenoid hypertrophy-related obstructive sleep apnea syndrome (OSAS) affects hematological inflammatory parameters in children. Specifically, this study focused on evaluating the mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), which have been proposed as potential biomarkers of systemic inflammation in various pediatric and adult airway disorders. Methods: A retrospective case-control analysis was performed, including children diagnosed with OSAS secondary to adenoid hypertrophy and age-matched healthy controls without respiratory symptoms. Complete blood count parameters, including MPV, platelet, lymphocyte, neutrophil, and white blood cell counts, were obtained from the medical records. Inflammatory markers (NLR and PLR) were calculated and compared between groups. Receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic performance of the significant hematological markers and to determine the optimal cutoff values. Results: A total of 129 pediatric patients were included in this study. The adenoidectomy group consisted of 61 children, while 68 children who underwent minor urological procedures served as controls. MPV, lymphocyte count, and PLR values did not differ significantly between the groups (p>0.05). However, hemoglobin levels were significantly lower in the OSAS group, whereas platelet count, white blood cell count, neutrophil count, and NLR were significantly higher (p

Keywords : Adenoid hypertrophy, obstructive sleep apnea syndrome, mean platelet volume, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio

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Article available in :
Volume 9, Issue 3, 2026
Page : 558-563
https://doi.org/10.32322/jhsm.1827947
Article Information
Received : 21 Kas 2025
Accepted : 25 Mar 2026
Published : 19 May 2026
Corresponding Author :

Fatma Bayburt: Department of Anesthesiology and Reanimation, Faculty of Medicine, Giresun University, Giresun, Turkiye

[email protected]
Citation : Alkan Bayburt F, Tamdoğan İ, Coşkun M, Bulut A. Comparison of blood count values in children with obstructive sleep apnea due to adenoid hypertrophy and those without apnea. J Health Sci Med. 2026;9(3):558-563. doi:10.32322/jhsm.1827947

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